What is Acenaphthylene?
Acenaphthylene is a colorless crystalline solid. Insoluble in water. Used in dye synthesis, insecticides, fungicides, and in the manufacture of plastics. CAMEO Chemicals. Acenaphthylene is a ortho- and peri-fused tricyclic hydrocarbon that occurs in coal tar.
Uses
Acenaphthylene is used to make products for electronic engineering and plastics and to make dyes.
Sources & Potential Exposure
Blood polycyclic aromatic hydrocarbon (PAH) levels in children, including acenaphthylene, significantly correlated with oxidative stress and altered antioxidant status. It induced cytokine production and reduced nitric oxide formation in human coronary artery endothelial cell cultures. Metabolic activation of PAHs and aryl- and heterocyclic amines to genotoxic products was examined in Salmonella typhimurium, and it was found that P450 2A13 and 2A6 (as well as P450 1B1) were able to activate several of these procarcinogens. Acenaphthylene is oxidized by human P450s 2A6 and 2A13 and other P450s to form several mono- and di-oxygenated products. It is not classifiable as to human carcinogenicity.
Federal Regulations
EPA: It is not classifiable as to human carcinogenicity